Helicobacter pylori infection
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged between 18-65 years; 2. Meet the diagnostic criteria for Helicobacter pylori infection or non- Helicobacter pylori infection; 3. PPI, H2RA and antibiotic treatments should be stopped two weeks before the 13C breath test or 14C breath test, and those who test positive for HP; 4. Patients who give informed consent and are willing to accept the trial.
Exclusion criteria
Exclusion criteria: 1. Patients with chronic atrophic gastritis with severe dysplasia, upper gastrointestinal bleeding, peptic ulcer and gastrointestinal tumor; 2. Organic diseases of the digestive system (such as chronic pancreatitis, liver cirrhosis, etc.), or other systemic diseases (such as hyperthyroidism, diabetes, chronic renal insufficiency, mental and neurological diseases, etc.); or other serious underlying diseases, Such as coronary heart disease, heart failure, liver and kidney failure; 3. Those who use drugs (antacids, H2RA, PPIs, antibiotics, etc.) that may affect the HP test results within 2 weeks; 4. Persons with severe allergies; 5. Women who are breastfeeding, pregnant or planning to become pregnant: 6. Persons who have serious bad habits such as smoking, alcohol or drugs; 7. Patients who need to take non-steroidal anti-inflammatory drugs for a long period of time cannot be ruled out for patients who interfere with other drugs; 8. Those who have poor compliance and difficulty in completing this experiment, which may affect the efficacy or safety judgment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Flora density;Cell Apoptosis;Flora structure; | — |
Countries
China
Contacts
Hubei University of Chinese Medicine