Breast Cancer
Conditions
Interventions
Sponsors
Liangning Cancer Hospital &Institute
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Female patients aged 18-70 years. 2) ECoG patients with general state <= 2. 3) Histologically confirmed invasive breast cancer. 4) The primary tumor was treated with modified radical mastectomy, and tumor stage: T1-2,N1. 5) Patients accepted at least 4 courses of adjuvant chemotherapy with anthracycline or taxane. 6) Radiotherapy must be performed sequentially after the completion of adjuvant chemotherapy, starting no later than 8 weeks after the end of chemotherapy. 7) There must be adequate systemic examination (such as chest X-ray, B-ultrasound, CT, etc.) within 2 months before randomization of radiotherapy to confirm that there is no distant metastasis. 8) The patient must have sufficient primary fresh frozen specimens or post-paraffin tissue sections for RecurIndex testing. 9) No previous history of malignant tumors, except for basal cell carcinoma of the skin. 10) Signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1) Postoperative radiotherapy was confirmed as T3-4, N0, N2-3, M1 lesion staging before enrollment. 2) Receive any new adjuvant therapy before surgery, including chemotherapy, endocrine therapy, targeted therapy or radiation therapy. 3) Patients who underwent total mastectomy and only sentinel lymph node biopsy. 4) Have a history of contralateral breast cancer. 5) History of chest radiotherapy. 6) Combined with severe heart, lung, liver, kidney, hematopoietic, neurological diseases, and mental illness. 7) Pregnant or lactating women.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| recurrence rate;Distant free survival;Overal survival; | — |
Countries
China
Contacts
Public ContactZhang Qiang
Liangning Cancer Hospital &Institute
Outcome results
None listed