Lung Disease
Conditions
Interventions
Traditional nasal low flow oxygen inhalation group:transnasal low-flow therapy by nasal cannulae
Sponsors
Shenzhen Second People's Hospital / The First Affiliated Hospital of Shenzhen University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged from 18 to 60 years old are going to receive wedge resection or lobectomy under thoracoscope under one lung ventilation; 2. Patients with one lung ventilation more than 1 hour during operation; 3. Informed and voluntary patients participated in this study and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Subjects with body mass index >= 30 kg / m2; 2. Patients with pulmonary infection before operation; 3. Subjects with nasal diseases who could not use nasal ventilation; 4. Subjects whose pulse oxygen saturation of air breathing is less than 96%; 5. Subjects with left lung surgery or estimated surgical range more than one lobe; 6. Patients with respiratory failure or adult respiratory distress syndrome before operation; 7. Patients with obstructive sleep apnea before operation; 8. Subjects with long-term smoking history (smoking more than one cigarette a day and continuously smoking for more than 6 months); 9. Patients with severe liver and kidney diseases (child Pugh grade C or preoperative dialysis patients); Albumin < 35g / L; 10. Subjects with preoperative cardiac function grade 3 or above; 11. Patients with history of abusing narcotic sedatives and analgesics; There are contraindications or allergies to the test drug and other narcotic drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of hypoxemia; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS;Breathing discomfort score;Ratio of patients needing continued respiratory support treatment;Rates of patients requiring endotracheal intubation or non-invasive ventilator treatment;Rates of pulmonary complication;Rates of patients who were transferred to ICU unplanned;Hospitalization days;In-hospital mortality; | — |
Countries
China
Contacts
Public ContactZhao Zhao
Shenzhen Second People's Hospital / The First Affiliated Hospital of Shenzhen University
Outcome results
None listed