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Acupuncture combined with ondansetron for prevention of postoperative nausea and vomiting in gynaecological patients undergoing laparoscopic surgery: a randomized controlled trial

Acupuncture combined with ondansetron for prevention of postoperative nausea and vomiting in gynaecological patients undergoing laparoscopic surgery: a randomized controlled trial.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100042486
Enrollment
Unknown
Registered
2021-01-22
Start date
2021-01-26
Completion date
Unknown
Last updated
2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative nausea and vomiting

Interventions

Sponsors

Beijing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Women aged 18-65 years; 2. Subjects with ASA grade I or II; 3. Patients scheduled for gynecological laparoscopic ovarian or uterine surgery under general anesthesia; 4. Patients who are expected to use opioids after operation; 5. Subjects whose estimated operation time (from anesthesia induction to wound closure) >= 1H; 6. Subjects who voluntarily participated in the trial and signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Pregnant, lactating or menstrual women and smoking women; 2. Patients scheduled for laparoscopic surgery for gynecological malignancies; 3. Patients with nausea, vomiting or both within 24 hours before operation; 4. Patients who received antiemetic drugs, opioids or glucocorticoids within 24 hours before operation; 5. Patients with severe hepatic and renal insufficiency, central nervous system injury, vertebrobasilar insufficiency, vestibular diseases, coagulation disorders or other blood diseases; 6. Patients with skin damage at acupuncture point or eczema and other skin diseases; 7. Subjects who participated in other studies in recent 3 months; 8. Patients known to be allergic to ondansetron or metoclopramide.

Design outcomes

Primary

MeasureTime frame
the incidence of PONV in the first 24 hours postoperative;

Secondary

MeasureTime frame
the incidence of PON, the incidence of POV and the incidence of PONV in other evaluation periods;degree of nausea;episodes of vomiting;pain intensity;assessment of total postoperative analgesics dosage;rescue antiemetic need;assessment of satisfaction score;credibility and expectancy;Time to first flatus;

Countries

China

Contacts

Public ContactCunzhi Liu

College of Acupuncture and Massage, Beijing University of Traditional Chinese Medicine

lcz_tg@126.com+86 15901261692

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026