Effect of remimazolam tosilate or propofol combined with remifentanil anesthesia on hemodynamics and Inflammation response in patients undergoing laparoscopic general anesthesia

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100042461

Enrollment

Unknown

Registered

2021-01-21

Start date

2020-11-30

Completion date

Unknown

Last updated

2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic surgery

Interventions

A:remimazolam tosilate (low dose)

B:remimazolam tosilate (high dose)

C:propofol

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: It is planned to select 90 patients undergoing elective laparoscopic surgery in this hospital, regardless of age, male and female, ASA II-III.

Exclusion criteria

Exclusion criteria: People who are known to be allergic to remazolam or have a history of severe allergies and family history, severe circulatory system diseases, mental diseases and neurological diseases, deafness and dumbness, alcoholism, respiratory diseases, abnormal liver and kidney function, abnormal blood coagulation, Patients with infections, lipometabolism, and those considered by researchers to be inappropriate to participate in this clinical study.

Design outcomes

Primary

Measure	Time frame
SBP;DBP;HR;MAP;PCT;IL-6;CRP;SAA;	—

Secondary

Measure	Time frame
operation time;Sufentanil dosage;Dosage of remifentanil;Wake up time;Dosage of phenylephrine;	—

Countries

China

Contacts

Public ContactZhang Yuenong

Surgical Anesthesia Center, Yuedong Hospital, Third Affiliated Hospital of Sun Yat-Sen University

36856665@qq.com+86 15986476688

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026