Acute ischemic stroke secondary to intracranial vascular obstruction
Conditions
Interventions
single arm:thrombus aspiration catheters
Sponsors
Beijing Tiantan Hospital affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) Aged >= 18 years, regardless of gender; 2) Acute ischemic stroke was confirmed by DSA to be intracranial internal carotid artery (ICA) or middle cerebral motility Occlusion of artery (MCA) M1 / M2 or anterior cerebral artery (ACA) A1 / A2; 3) mRS score 0 ~ 1 before onset; 4) Preoperative NIHSS score >= 6; 5) CT or MRI based ASPECT score >= 6; 6) The time from onset to puncture shall be within 6 hours; 7) The patient or legal guardian signs the informed consent.
Exclusion criteria
Exclusion criteria: 1) CT or MRI suggested intracranial hemorrhage (SWI microhemorrhage was not considered); 2) CT or MRI indicated large cerebral infarction (ASPECT score MCA)1/3 of the blood supply area or the infarcted volume was > 70ml); 3) DSA suggested vascular occlusion of bilateral carotid artery system; 4) DSA suggested tortuous vascular path, and the instrument was difficult to reach the target vessel; 5) The target vessel is known to be chronic occlusion; 6) Those who are known to be severely allergic to contrast agents (excluding rashes); 7) refractory hypertension beyond drug control, defined as systolic bp > 185mmHg or diastolic bp > 110 MMHG. 8) Baseline blood glucose 3 Or platelet count < 40 x 10^9/L; 10) There is known to be severe heart, lung, liver and kidney failure or other serious disease (such as an untreated intracranial swelling, aneurysms, intracranial aneurysms or arteriovenous malformations); 11) Patients with mental illness; 12) A history of major surgery 30 days before enrollment; 13) Life expectancy < 90 days; 14) Pregnant or lactating women; 15) Is participating in any other drug or medical device clinical trial, or may be after being enrolled in this clinical trial To participate in clinical trials of any other drug or medical device; 16) The researcher judged that there were other conditions that were not suitable for the group.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The success rate of target vessel confirmed by DSA immediately after surgery (mTICI 2B-3).; | — |
Countries
China
Contacts
Public ContactNing Ma
Beijing Tiantan Hospital affiliated to Capital Medical University
Outcome results
None listed