Effect of targeted temperature management on cerebral autoregulation in patients with neurocritical diseases

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100042457

Enrollment

Unknown

Registered

2021-01-21

Start date

2021-01-22

Completion date

Unknown

Last updated

2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

aneurysmal subarachnoid hemorrhage, ischemic stroke, hemorrhagic stroke, traumatic brain injury

Interventions

case series:N/A

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Aneurysmal subarachnoid hemorrhage (aSAH), Traumatic brain injury (TBI), acute ischemic stroke (AIS), Intracerebral hemorrhage (ICH), Ischemic hypoxic encephalopathy (HIE), Sepsis associated encephalopathy (SAE) who need to reduce the core temperature to normal.

Exclusion criteria

Exclusion criteria: (1) Aged < 18 years; (2) Pregnancy; (3) The temporal window was limited and the image could not be obtained; (4) Patients with bradycardia induced by common carotid artery compression and intolerant of THRT; (5) Patients with severe carotid artery disease; (6) Uncorrected severe coagulation disorders and active bleeding; (7) Patients without informed consent; (8) Patients who had been treated with hypothermia before inclusion.

Design outcomes

Primary

Measure	Time frame
cerebral autoregulation;	—

Countries

China

Contacts

Public ContactLina Zhang

Xiangya Hospital of Central South University

zln7095@163.com+86 15874875763

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026