Clinical study on analgesic effect of cocktail drugs in rhinoplasty with autologous costal cartilage

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100042445

Enrollment

Unknown

Registered

2021-01-21

Start date

2021-02-01

Completion date

Unknown

Last updated

2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rhinoplasty with autologous costal cartilage

Interventions

A:ropivacaine, Parecoxib, betamethasone and epinephrine.

B:ropivacaine

C:ropivacaine and PCA

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: (1) Patients requiring initial rhinoplasty with autologous costal cartilage ; (2) Aged 18 to 60 years; (3) body mass index was 20~35 kg/m2; (4) the American Society of Anesthesiologists (ASA) classification (anesthesia risk assessment) is I ~ III level; (5) the patient signed the informed consent.

Exclusion criteria

Exclusion criteria: (1) Alcohol or drug abuse and and allergic to any drugs in this trial; (2) long-term opioid users(opioids were used daily or almost daily for more than 3 months); (3) language impairment and inability to perform pain numerical scales (NRS); (4) local skin infection and bleeding at the puncture site of anesthesia; (5) patients considered unfit for inclusion by the surgeon or anesthesiologist.

Design outcomes

Primary

Measure	Time frame
VAS pain score;	—

Secondary

Measure	Time frame
Time of first postoperative analgesia;	—

Countries

China

Contacts

Public ContactFan Fei

Peking Union Medical College Plastic Hospital

wxinplastic@163.com+86 13311231331

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 12, 2026