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Hydromorphone in the treatment of perioperative pain during embolization of advanced malignant tumors: a randomized controlled clinical study

Hydromorphone in the treatment of perioperative pain during embolization of advanced malignant tumors: a randomized controlled clinical study

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100042421
Enrollment
Unknown
Registered
2021-01-21
Start date
2021-01-18
Completion date
Unknown
Last updated
2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative pain

Interventions

Group A:Hydromorphone PCIA
Group B:0.9% Normal Saline

Sponsors

Chengdu Qingbaijiang District People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: (1) Volunteer to participate and sign the informed consent in writing; (2) Patients with advanced malignant tumors undergoing selective tumor embolization; (3) The activity status score established by the Eastern Cooperative Oncology Group (ECOG) <= 2 points; (4) The expected survival period is greater than 3 months.

Exclusion criteria

Exclusion criteria: (1) Severe coagulation disorder that cannot be corrected; (2) History of serious cardiovascular and respiratory diseases; (3) Patients who are allergic to test drugs or contrast agents; (4) Patients with opioid addiction; (5) Patients with cognitive dysfunction; (6) Those who have participated in other clinical research in the past 30 days. (7) The sponsor or investigator directly involved in the trial or their family members; (8) Those who are judged by the investigator to be unsuitable to participate in this trial.

Design outcomes

Primary

MeasureTime frame
Numerical Rating Scale;

Secondary

MeasureTime frame
Satisfaction evaluation;Number of breakthrough pain per day;Postoperative hospital stay;Incidence of adverse reactions;

Countries

China

Contacts

Public ContactCao lei

Chengdu Qingbaijiang District People's Hospital

327511253@qq.com+86 13880208081

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026