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Effect of Body mass index on the plasma concentration and pharmacodynamics of propofol with target-controlled infusion

Effect of Body mass index on the plasma concentration and pharmacodynamics of propofol with target-controlled infusion

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100042395
Enrollment
Unknown
Registered
2021-01-21
Start date
2021-03-01
Completion date
Unknown
Last updated
2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia

Interventions

Normal weight group:Nil
overweight group :Nil
Obesity group:Nil

Sponsors

Changzhou Second People's Hospital Affiliated to Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients meeting the indications of total intravenous anesthesia, 2. American Society of anesthesiologists (ASA) classification: I or II. 3. Patients aged 18-70 years.

Exclusion criteria

Exclusion criteria: 1. Patients with a history of smoking and drinking; 2. Subjects with abnormal heart, lung, liver and kidney function; 3. Patients with mental system diseases or other diseases affecting propofol metabolism, such as hyperthyroidism, endocrine dysfunction, etc.; 4. Subjects taking sedative hypnotic drugs for a long time and taking liver drug enzyme inducer or inhibitor within one month before operation.

Design outcomes

Primary

MeasureTime frame
Induction time;Sedative effect indicators during recovery;—

Countries

China

Contacts

Public ContactJingjing Shang

Changzhou Second People's Hospital Affiliated to Nanjing Medical University

shang0308@126.com+86 13921032480

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026