Allergic rhinitis
Conditions
Interventions
Sponsors
Hospital of Chengdu University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Male
Age
10 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Subjects aged from 10 to 60 years, regardless of gender; 2. For patients with allergic rhinitis, the diagnostic criteria (ARIA) are as follows: Symptoms: sneezing, clear water like runny nose, itchy nose and stuffy nose appeared 2 or more symptoms, lasting or accumulating for more than 1 hour every day; Signs: common nasal mucosa pale, edema, nasal water secretion; Allergen test: at least one allergen SPT and / or serum specific IgE positive (all results within one year are valid); 3. Patients with lung qi deficiency syndrome, spleen qi deficiency syndrome or lung spleen qi deficiency syndrome; 4. Patients with symptom onset >= 4 days / week, and >= 4 consecutive weeks; 5. Patients with moderate to severe allergic rhinitis have a significant impact on the quality of life (including sleep, daily life, study or work); 6. Patients with nasal symptom score (TNSS) >= 8 within 12 hours, nasal congestion score >= 2; 7. Patients and guardians informed and agreed to participate in the study.
Exclusion criteria
Exclusion criteria: 1. Patients with nasal space occupying lesions and structural abnormalities, including but not limited to: nasal polyps, nasal masses, meningeal encephalocele, congenital nostril atresia, congenital piriform foramen stenosis, thickening and internal displacement of maxillary frontal process, deviation of nasal septum, gasification of middle turbinate, etc; 2. Patients with known poor overall physical condition include but are not limited to: (1) Malignant tumor; (2) Uncontrolled systemic infection; (3) Severe malnutrition (BMI = 7.0 mmol / L or 2-hour postprandial glucose >= 11.1 mmol / L after standardized treatment) was found in diabetic patients; (5) The blood pressure of hypertension patients was poorly controlled (systolic blood pressure >= 160 mmHg and / or diastolic blood pressure >= 100 mmHg after standardized treatment); (6) Moderate to severe anemia (HB = 1.5unl, creatinine >= 1.5unl, AST, ALT >= 1.5unl; 3. Pregnant or lactating women; 4. Subjects who are known or suspected to be allergic to the components of Tongqiao Biyan granules; 5. Subjects with a history of nose or eye injury or surgery in the past three months; 6. Subjects dependent on nasal, oral or ocular decongestants, antihistamines and hormones; 7. Subjects with a history of mental illness (except mild mood disorders); 8. The subjects with dyslexia or communication difficulties can not cooperate to complete the study; 9. Subjects who can't guarantee medication compliance or can't return visit on time; 10. Situations that other researchers believe may seriously affect the research results.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TNSS; | — |
Secondary
| Measure | Time frame |
|---|---|
| TOSS;Effective after 3 weeks of treatment;RQLQ;Anterior rhinoscopy score;IL4;IL5;TGF-ß;AE; | — |
Countries
china
Contacts
Public ContactTian Li
Affiliated Hospital of Chengdu University of Traditional Chinese Medicine
Outcome results
None listed