Lumbar Disc Herniation
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients who meet the diagnostic criteria of lumbar disc herniation; 2. Patients aged 20-65 years old (inclusive), regardless of gender; 3. Subjects with unilateral L4 / 5 or L5 / S1 disc herniation by lumbar magnetic resonance or CT examination; 4. Patients with a history of more than 2 weeks and less than 6 months; 5. Patients with VAS score >= 3; 6. Patients who understand and agree to participate in this study and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with other major lumbar diseases, such as tumor, tuberculosis, etc.; 2. Patients with acute lumbar injury and pain caused by trauma or operation; 3. Patients with cardiovascular, lung, kidney, hematopoietic system and other major diseases; 4. Mental patients; 5. Patients with osteoporosis; 6. Pregnant or lactating women; 7. Patients with contraindications to oral celecoxib; 8. Subjects with contraindications of MRI.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improved Oswestry dysfunction index;The Visual Analog Scale (VAS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Dosage of celecoxib;Assessment of muscle tissue status (compliance);Muscle surface EMG signal; 3D motion capture assessment; | — |
Countries
China
Contacts
Yueyang Integrated Traditional Chinese and Western Medicine Hospital affiliated to Shanghai University of Traditional Chinese Medicine