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Clinical study of tuina based on the mechanical characteristics of key lumbar muscle groups combined with celecoxib in the treatment of lumbar disc herniation

Clinical study of tuina based on the mechanical characteristics of key lumbar muscle groups combined with celecoxib in the treatment of lumbar disc herniation

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100042390
Enrollment
Unknown
Registered
2021-01-21
Start date
2021-03-01
Completion date
Unknown
Last updated
2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar Disc Herniation

Interventions

Sponsors

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients who meet the diagnostic criteria of lumbar disc herniation; 2. Patients aged 20-65 years old (inclusive), regardless of gender; 3. Subjects with unilateral L4 / 5 or L5 / S1 disc herniation by lumbar magnetic resonance or CT examination; 4. Patients with a history of more than 2 weeks and less than 6 months; 5. Patients with VAS score >= 3; 6. Patients who understand and agree to participate in this study and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with other major lumbar diseases, such as tumor, tuberculosis, etc.; 2. Patients with acute lumbar injury and pain caused by trauma or operation; 3. Patients with cardiovascular, lung, kidney, hematopoietic system and other major diseases; 4. Mental patients; 5. Patients with osteoporosis; 6. Pregnant or lactating women; 7. Patients with contraindications to oral celecoxib; 8. Subjects with contraindications of MRI.

Design outcomes

Primary

MeasureTime frame
Improved Oswestry dysfunction index;The Visual Analog Scale (VAS);

Secondary

MeasureTime frame
Dosage of celecoxib;Assessment of muscle tissue status (compliance);Muscle surface EMG signal; 3D motion capture assessment;

Countries

China

Contacts

Public ContactSun Wuquan

Yueyang Integrated Traditional Chinese and Western Medicine Hospital affiliated to Shanghai University of Traditional Chinese Medicine

yyyytnk@163.com+86 21-65161782

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026