Postoperative pain after second cesarean section
Conditions
Interventions
Experimental group (group NS1):intravenous injection of nalbuphine 10mg before oxytocin infusion combined sufentanil 2ug/kg PCIA
Experimental group (group NS2):intravenous injection of nalbuphine 20mg before oxytocin infusion combined sufentanil 2ug/kg PCIA
Experimental group (group NS3):intravenous injection of nalbuphine 30mg before oxytocin infusion combined sufentanil 2ug/kg PCIA
Control group (group S):sufentanil 2ug/kg PCIA
Sponsors
Yunnan First People's Hospital Affiliated to Kunming University of Science and Technology
Eligibility
Sex/Gender
Female
Age
22 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. The second cesarean section; 2. Subjects of 37 weeks <= gestational age < 42 weeks; 3. Subjects aged 20-40 years old weighing 52-85kg; 4. Subjects of ASA grade I - II; 5. Subjects under subarachnoid anesthesia; 6. Subjects who did not take opioids before operation.
Exclusion criteria
Exclusion criteria: 1. Subjects with contraindications to intraspinal anesthesia; 2. Subjects with history of allergy to local anesthetics and opioids; 3. Subjects of opioid abuse; 4. Subjects with severe organic diseases or coagulation dysfunction; 5. Subjects who changed the operation mode or anesthesia method during the operation; 6. Subjects with the possibility of massive hemorrhage such as placental abruption, placenta previa and preeclampsia; 7. Patients with mental illness; 8. Subjects who lost follow-up or dropped out of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| The number of PCIA pressing time;The sufentanil consumption;The intensity of uterine contraction;the incidence of adverse reactions; | — |
Countries
China
Contacts
Public ContactHua Jin
Yunnan First People's Hospital Affiliated to Kunming University of Science and Technology
Outcome results
None listed