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Clinical study of botulinum toxin type A injection for surgical incision scar based on expanding the area to tension-reducing

botulinum toxin type A injection for surgical incision scar

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100042378
Enrollment
Unknown
Registered
2021-01-21
Start date
2021-01-25
Completion date
Unknown
Last updated
2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

surgical incision scar

Interventions

Experimental sides A:Botulinum toxin A was injected in multiple rows on both sides of the incision
Experimental sides B:Botulinum toxin A was injected in multiple rows on both sides of the incision
Control sides A:Botulinum toxin A was injected in single rows on both sides of the incision
Control sides B:Botulinum toxin A was injected in single rows on both sides of the incision

Sponsors

The First Affiliated Hospital of Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: (1) The incision type was class I surgical incision, and plastic surgery suture was performed on all of them. The length of postoperative body surface scar was > 4cm; (2) Aged 16-60 years; (3) No radiotherapy, pressure therapy and other adjuvant treatments were received at the surgical incision; (4) Not receiving any form of BTXA treatment within 6 months; (5) Signing the informed consent.

Exclusion criteria

Exclusion criteria: (1) Patients with a history of diabetes, cardiovascular disease and other chronic systemic diseases; (2) Patients with history of keloid; (3) Patients with malignant tumors; (4) Severe systemic diseases; (5) Pregnant or lactating women; (6) patients who cannot tolerate surgery; (7) Other patients with contraindications to Botox A for injection; (8) Other circumstances deemed unsuitable for inclusion.

Design outcomes

Primary

MeasureTime frame
Scar width;The Vancouver Scar Scale;Visual Analogue Scale for scar condition;

Countries

China

Contacts

Public ContactLi Guangshuai

The First Affiliated Hospital of Zhengzhou University

liguangshuai@zzu.edu.cn+86 13838062386

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026