Rectal cancer
Conditions
Interventions
Experimental group:Lower ligation of the inferior mesenteric artery
Control group:Higher ligation of the inferior mesenteric artery
Sponsors
The First Affiliated Hospital of Air Force Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Subjects aged 18-75 years; 2. Adenocarcinoma of the rectum was confirmed by pathology; 3. Electronic hard mirror examination and/or MR assessment of tumor within 10cm from anus; 4. Laparoscopic radical anterior resection of rectal cancer is proposed; 5. ECOG (Eastern Cooperative Oncology Group) determined the clinical status as 0-2; 6. Sign the consent form.
Exclusion criteria
Exclusion criteria: 1. Distant metastasis of tumor; 2. Violation of the principle of randomization or ileostomy; 3. A history of intractable constipation or inflammatory bowel disease; 4. Patients with severe cardiovascular and cerebrovascular, liver and kidney diseases and abnormal liver and kidney functions; 5. Rectal anastomotic stenosis was followed up after operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bowel function;3 year progression-free survival (PFS); | — |
Secondary
| Measure | Time frame |
|---|---|
| 3 year overall survival (OS); | — |
Countries
China
Contacts
Public ContactJianyong Zheng
The First Affiliated Hospital of Air Force Medical University
Outcome results
None listed