The neural mechanisms of visual working memory impairment in patients with basal ganglia hemorrhage

Constructing the GOS prediction model of patients with intracerebral hemorrhage using multimodal clinical data and machine learning

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100042345

Enrollment

Unknown

Registered

2021-01-19

Start date

2021-02-01

Completion date

Unknown

Last updated

2021-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spontaneous intracerebral hemorrhage

Interventions

Intracerebral hemorrhage group:visual working memory test

healthy control group:visual working memory test

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients with a diagnosis of basal ganglia hemorrhage confirmed by computerized tomography (CT); aged between 18 and 70 years; with no history of mental disorder; without aphasia and consciousness disorder; MMSE score is above 23; with normal or corrected to normal sight and color perception; with no diagnosis of cerebral atrophy; can understand and follow the instruction; medically stable and consent to participate in will be recruited in this study. Control subjects will be recruited following these inclusion criteria: no history of mental and consciousness disorder; without any brain structure damage or disease identified by MRI or CT examinations; with normal or corrected to normal sight and color perception; age, gender, blood pressure and socioeconomically matched with ICH group; can follow the instruction and consent to participate in.

Exclusion criteria

Exclusion criteria: Participates will be ruled out if they meet any criteria listed below: have any MRI contraindications, such as having metallic foreign bodies or a heart pacemaker; tumors or other clinically significant diseases; the amount of bleeding is less than 5 ml or more than 30 ml; hemorrhage caused by aneurysms, traumatic injury or hemorrhagic conversion of a cerebral infraction; bad quality of neuroimaging data due to head movement (over 3 mm) or artifact; can not understand or follow the instruction.

Design outcomes

Primary

Measure	Time frame
response error of working memory;	—

Secondary

Measure	Time frame
fractional anisotropy;Regional homogeneity;amplitude of low frequency fluctuation;degree centrality;	—

Countries

China

Contacts

Public ContactQinghua Zhang

Huazhong University of Science and Technology Union Shenzhen Hospital

doctorzhanghua@163.com+86 18899775790

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026