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A prospective study on the effect of circumcision on the conservative treatment of vesicoureteral reflux in children conducted by using propensity score method and support vector machine model

A prospective study on the effect of circumcision on the conservative treatment of vesicoureteral reflux in children conducted by using propensity score method and support vector machine model

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100042319
Enrollment
Unknown
Registered
2021-01-19
Start date
2021-01-19
Completion date
Unknown
Last updated
2021-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

vesicoureteral reflux

Interventions

3:Continuous antibiotic prophylaxis+circumcision
4:Wait and Watch

Sponsors

Shanghai Children's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
No minimum to 3 Years

Inclusion criteria

Inclusion criteria: Children with VUR under 3 years-old.300 cases were screened by outpatient program of nephrology and urology department, including: 1) VCUG was performed after the first fUTI; 2) Screening for fetal hydronephrosis: VCUG for severe hydronephrosis (SFU III-IV), repetitive kidney with hydronephrosis, ureterocele, ureterectasia, and abnormal bladder; 3) Children with VUR detected by family screening. Eventually, there were about 200 cases.

Exclusion criteria

Exclusion criteria: Other malformations such as ureteropelelic junction stricture, ureteral junction stricture, ectopic ureter opening, giant ureter, dysplastic kidney, abnormal echo of renal parenchyma, duplicate kidney, horseshoe-kidney, etc. were excluded, except chromosomal abnormalities or other structural abnormalities.

Design outcomes

Primary

MeasureTime frame
Urine routine, serum creatinine;Renal ultrasound;VCUG;Isotope Renogram;

Countries

China

Contacts

Public ContactHuang Yichen

Shanghai Children's Hospital

huangyc@shchildren.com.cn+86 18930597225

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026