Preoperative sedation in children
Conditions
Interventions
A:Remazolam besylate 0.3mg/kg
B:Remazolam besylate 0.4mg/kg
C:Remazolam besylate 0.5mg/kg
D:Midazolam 0.2 mg / kg
E:Normal saline 1ml
Sponsors
Yichang Central People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: a) The operation included adenoidectomy with (or without) tonsillectomy, laparoscopic high ligation of inguinal hernia sac, resection of body surface tumor, circumcision and penile lengthening; b) Aged 2-7 years, regardless of gender; c) ASA grade I ~ II; d) The parents or legal guardians of the children signed the informed consent.
Exclusion criteria
Exclusion criteria: a) Body mass index (BMI): BMI >= 28KG / m2 or = 28KG; b) Analgesic and sedative drugs, antiemetic drugs and anti pruritus drugs were used 24 hours before operation; c) Children whose body temperature was higher than 38 degrees C within 24 hours before operation or accompanied with symptoms of acute upper respiratory tract infection; d) Children with history of bronchial asthma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Basal blood pressure;Basal heart rate;Basic finger pulse oxygen saturation;Blood pressure 5 minutes after administration;Heart rate 5 minutes after administration;Pulse oxygen saturation 5 minutes after administration;Sedation score 5 minutes after administration;Blood pressure 10 minutes after administration;Heart rate 10 minutes after administration;Sedation score 10 minutes after administration;Pulse oxygen saturation 10 minutes after administration;Blood pressure 15 minutes after administration;Heart rate 15 minutes after administration;Pulse oxygen saturation 15 minutes after administration;Sedation score 15 minutes after administration; | — |
Countries
China
Contacts
Public ContactGong Yuan
Yichang Central People's Hospital
Outcome results
None listed