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Efficacy and safety of alfentanil for perioperative analgesia in children undergoing laparoscopic surgery

Efficacy and safety of alfentanil for perioperative analgesia in children undergoing laparoscopic surgery

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100042286
Enrollment
Unknown
Registered
2021-01-17
Start date
2021-02-01
Completion date
Unknown
Last updated
2021-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative pain of laparoscopic surgery in children

Interventions

A:Alfentanil 10 µ g / kg
B:Alfentanil 20 µ g / kg
C:Alfentanil 30 µ g / kg
D:Sufentanil 0.3 µ g / kg

Sponsors

Yichang Central People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Age: 1-7 years old, regardless of gender; 2) ASA grade I ~ II; 3) Children scheduled for laparoscopic surgery (tracheal intubation general anesthesia); 4) The estimated anesthesia operation time is less than or equal to 45 min;

Exclusion criteria

Exclusion criteria: 1) Body mass index (BMI): BMI >= 28KG / m2 or = 28kg; 2) Children with history of opioid allergy; 3) Analgesic and sedative drugs, antiemetic drugs and anti pruritus drugs were used 24 hours before operation; 4) Children whose body temperature was higher than 38 degrees C within 24 hours before operation or accompanied with symptoms of acute upper respiratory tract infection; 5) Children with history of bronchial asthma;

Design outcomes

Primary

MeasureTime frame
Basal blood pressure;Basal heart rate;Blood pressure before anesthesia;Heart rate before anesthesia;Blood pressure after tracheal intubation;Heart rate after tracheal intubation;Blood pressure during skin incision;????? ????? Heart rate during skin incision;Recovery time;

Countries

China

Contacts

Public ContactGong Yuan

Yichang Central People's Hospital

gy-yc@163.com+86 13986746821

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026