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Integrative and comparative multiomics identify biomarkers for early detection of colorectal cancer

Integrative and comparative multiomics identify biomarkers for early detection of colorectal cancer

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100042244
Enrollment
Unknown
Registered
2021-01-17
Start date
2021-02-01
Completion date
Unknown
Last updated
2021-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colon Cancer

Interventions

Colon cancer group:Nil
Ulcerative colitis group:Nil
Colorectal Adenomas group:Nil

Sponsors

Shanghai Tenth People's Hospital Affiliated to Tongji University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Ages Eligible for Study: 25 Years to 75 Years (Adult, Older Adult); Sexes Eligible for Study: All (2) Diagnosis of Adenoma, ulcerative colitis or colon cancer; (3) Eastern Cooperative Oncology Group (ECOG) Performance Status (PS):0-1; (4) Able to understand and willing to sign written informed consent form; (5) There is a supervisor who can be contacted regularly to report the subject's clinical / mental status.

Exclusion criteria

Exclusion criteria: (1) Subjects with active viral or bacterial infections that cannot be controlled by anti infective therapy; (2) Known history of human immunodeficiency virus infection or current chronic or active hepatitis B or C infection requiring treatment with antiviral therapy; (3) Subjects with autoimmune diseases or extremely low immunity, or other diseases requiring systemic immunosuppressive drugs or hormones; (4) Subjects with any other serious diseases The researchers believe that it may affect the treatment, follow-up or evaluation of patients. Including any uncontrollable neurological, psychiatric, immune regulatory, metabolic and infectious diseases; (5) Women who are pregnancy or breast-feeding; (6) Antibacterial or probiotic treatment 4 weeks before enrollment; (7) Subjects with history of alcohol or drug abuse within 3 months before enrollment; (8) Participated in any experimental drug program in the past 12 weeks; (9) Used immunosuppressive agents or chemotherapy in the past two years; (10) Ineligible patients according to the investigator's judgement.

Design outcomes

Primary

MeasureTime frame
Single-cell Sequencing;

Countries

China

Contacts

Public ContactHuanlong Qin

Shanghai Tenth People's Hospital Affiliated to Tongji University

wangjifeng@fudan.edu.cn+86 13761759562

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026