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Effects of sub-anaesthetic doses of esketamine on acute and chronic pain and recovery quality after thoracoscopic partial lung resection

Effects of sub-anaesthetic doses of esketamine on acute and chronic pain and recovery quality after thoracoscopic partial lung resection

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100042239
Enrollment
Unknown
Registered
2021-01-17
Start date
2021-02-01
Completion date
Unknown
Last updated
2022-03-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain and recovery after thoracic laparoscopic surgery

Interventions

Esketamine group:After induction of anesthesia, a single bolus of esketamine was injected
and the esketamine was continuously injected when the skin was cut
Control group:An equal volume of normal saline was given intravenously

Sponsors

Jinling Hospital, Nanjing, China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Aged 18-80 years; 2.ASA I-III; 3.Thoracoscopic lung surgery under general intravenous anesthesia; 4.Patients with postoperative patient-controlled intravenous analgesia pump (PCIA) treatment; 5.The patient voluntarily participats in this trial and signs an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Esketamine allergy; 2. Mental illness; 3. Elevated blood pressure of the patient will have adverse consequences (pheochromocytoma, aortic dissection, hyperthyroidism, etc.); 4. Heart, liver, and kidney dysfunction; 5. Craniocerebral surgery; 6. Glaucoma; 7. Drug or alcohol abuse; 8. Other reasons in which the researcher thinks it cannot be selected.

Design outcomes

Primary

MeasureTime frame
Visual analogue scale of pain;Recovery quality score;

Secondary

MeasureTime frame
Consumption of opioids after surgery;Side effects assessment;

Countries

China

Contacts

Public ContactShen Jinchun

Jinling Hospital, Nanjing, China

yyshen0203@163.com+86 15895990011

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026