Evaluation of renal function by contrast-enhanced ultrasound

Clinical study protocol for dynamic evaluation of renal function in patients with acute kidney injury by contrast-enhanced ultrasound

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100042234

Enrollment

Unknown

Registered

2021-01-16

Start date

2021-02-01

Completion date

Unknown

Last updated

2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Kidney Injury

Interventions

Gold Standard:2012 KDIGO Clinical Practice Guidelines for Acute Kidney Injury.

Index test:Renal contrast ultrasound/Cys-C/urine NGAL.

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Patients meeting the diagnostic criteria of 2016 international sepsis / septic shock management guidelines; 2. Patients aged over 18 years.

Exclusion criteria

Exclusion criteria: 1. Patients with chronic kidney disease, history of blood purification, kidney transplantation, renal benign / malignant tumor, renal vascular disease, chronic heart failure and severe liver disease before admission; 2. Patients who are expected to live in ICU for less than 48 hours or die within 72 hours; 3. Patients who refused continuous renal replacement therapy; 4. Patients who could not stop continuous renal replacement therapy due to the change of their condition; 5. Patients allergic to sulfur hexafluoride.

Design outcomes

Primary

Measure	Time frame
WIR;PIT;AUC;PSI;NGAL;CYS-C;	—

Countries

China

Contacts

Public ContactXu Lei

Tianjin Third Central Hospital

nokia007008@163.com+86 13032288771

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026