autoimmune encephalitis
Conditions
Interventions
NMDAR encephalitis group vs. healthy control goup:Nil
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
12 Years to 46 Years
Inclusion criteria
Inclusion criteria: The participants are prospectively recruited from the follow-up of the Outcome of anti-NMDAR Encephalitis Study in Western China (ONE-WC) study, in which treatment naive patients with NMDAR encephalitis at initial onset had been diagnosed based on definitions of autoimmune encephalitis from a recent consensus statement.
Exclusion criteria
Exclusion criteria: The exclusion criteria for patients and HCs were as follows: 1. Subjects who received antibiotics or probiotics, prebiotics or any immunotherapy within 1 month before sampling; 2. Subjects who experienced obvious abdominal pain, abdominal distension, diarrhea or respiratory tract infection within one month before sampling; 3. Subjects who abuse or rely on alcohol or other substances (except tobacco) within 3 months before enrollment; 4. Subjects with hypertension, diabetes and other chronic diseases; 5. Subjects with history of other autoimmune diseases (rheumatoid arthritis, systemic lupus erythematosus, type 1 diabetes, etc.); 6. Subjects with a history of intestinal surgery; 7. Pregnant or lactating subjects; and 8. Subjects with a history of neuropsychiatric diseases [depression, anxiety, schizophrenia, multiple sclerosis, etc.].
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| functional ability, and clinical relapse; | — |
Countries
China
Contacts
Public ContactZhen Hong
West China Hospital of Sichuan University
Outcome results
None listed