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The relationship between intracranial aneurysms and periodontitis: a cohort study

The relationship between intracranial aneurysms and periodontitis: a cohort study

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100042207
Enrollment
Unknown
Registered
2021-01-15
Start date
2021-06-01
Completion date
Unknown
Last updated
2021-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intracranial aneurysms, periodontitis

Interventions

Group of intracranial aneurysms:endovascular treatment
Group of non-intracranial anerysms:None

Sponsors

Beijing Tiantan Hospital Affiliated to Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with intracranial aneurysms confirmed by CTA, MRA or DSA; 2. Subjects aged >= 18 years and <= 75 years; 3. Subjects with at least 6 fully erupted teeth and at least 1 tooth in each quadrant of the oral cavity; 4. The subjects who signed the informed consent can complete the clinical trial as required. The subjects or their families agreed to sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients who have received periodontal treatment within one year; 2. Patients with intracranial aneurysms who have been treated or will be treated by craniotomy; 3. Patients with family history of intracranial aneurysm; 4. Subjects had other intracranial vascular malformations such as AVM, AVF, etc; 5. Subjects with aneurysms associated with blood bubble, dissection, fusiform, traumatic, infectious or cerebrovascular malformation; 6. Subjects with malignant tumors in the brain or other parts of the body; 7. Patients with severe mental illness cannot communicate when they are diagnosed with the disease; 8. The life expectancy of the subjects with poor general condition is less than 1 year; 9. Subjects who had participated in clinical trials of other drugs or medical devices before enrollment but failed to reach the main research end point; 10. Patients who cannot receive complete follow-up; 11. Pregnant women and female patients preparing for pregnancy during the follow-up period; 12. Patients with previous drug abuse history or drug abuse during follow-up period; 13. Patients scheduled for major surgery within 30 days before or 90 days after enrollment; 14. Patients who are not suitable to participate or continue to participate in this clinical trial.

Design outcomes

Primary

MeasureTime frame
Periodontitis;mRS score 12 months after treatment;

Countries

China

Contacts

Public ContactAihua Liu/ Hao Wang

Beijing Tiantan Hospital Affiliated to Capital Medical University

liuaihuadoctor@163.com+86 15901398688

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026