Intracranial aneurysms, periodontitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with intracranial aneurysms confirmed by CTA, MRA or DSA; 2. Subjects aged >= 18 years and <= 75 years; 3. Subjects with at least 6 fully erupted teeth and at least 1 tooth in each quadrant of the oral cavity; 4. The subjects who signed the informed consent can complete the clinical trial as required. The subjects or their families agreed to sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients who have received periodontal treatment within one year; 2. Patients with intracranial aneurysms who have been treated or will be treated by craniotomy; 3. Patients with family history of intracranial aneurysm; 4. Subjects had other intracranial vascular malformations such as AVM, AVF, etc; 5. Subjects with aneurysms associated with blood bubble, dissection, fusiform, traumatic, infectious or cerebrovascular malformation; 6. Subjects with malignant tumors in the brain or other parts of the body; 7. Patients with severe mental illness cannot communicate when they are diagnosed with the disease; 8. The life expectancy of the subjects with poor general condition is less than 1 year; 9. Subjects who had participated in clinical trials of other drugs or medical devices before enrollment but failed to reach the main research end point; 10. Patients who cannot receive complete follow-up; 11. Pregnant women and female patients preparing for pregnancy during the follow-up period; 12. Patients with previous drug abuse history or drug abuse during follow-up period; 13. Patients scheduled for major surgery within 30 days before or 90 days after enrollment; 14. Patients who are not suitable to participate or continue to participate in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Periodontitis;mRS score 12 months after treatment; | — |
Countries
China
Contacts
Beijing Tiantan Hospital Affiliated to Capital Medical University