recurrent implantation failure
Conditions
Interventions
experimental group:Perform the first regular dose of dydrogesterone (20mg BID) hormone replacement cycle endometrium electron microscopy, take three intima (P+4, P+6, P+8)
experimental group:High-dose dydrogesterone (40mg BID) was used for intimal transformation, and endometrial electron microscopy was performed again to observe the change of pinocytosis index on P+6 da
Sponsors
Zhejiang Provincial People's Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Aged >= 20 and = 3, none of them were pregnant; the endometrial thickness on the previous transplantation day was >= 8mm; willing to accept electron microscopy.
Exclusion criteria
Exclusion criteria: B-ultrasound excludes uneven endometrial echo, endometrial polyps, adenomyosis, and hydrosalpinx; excludes patients with endometriosis r-AFS stage III or higher; no hyperprolactinemia, polycystic ovary Syndrome, abnormal thyroid function, history of autoimmune disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| P+6 day pinocytosis count and the proportion of various types of pinocytosis, pinocytosis index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Morphology of Uterine Cavity Epithelium by Transmission Electron Microscope; | — |
Countries
China
Contacts
Public ContactJing Shu
Zhejiang Provincial People's Hospital
Outcome results
None listed