Nutrition
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients who are comatose or unable to awake in a short period of time, or have dysphagia in conscious patients; 2. Male or non pregnant women aged 18-65 years; 3. Enteral nutrition can be started within 24-48 hours after hospitalization.
Exclusion criteria
Exclusion criteria: 1. Gastrointestinal bleeding was obvious, and hemoglobin level decreased progressively; 2. Hemodynamics is unstable and the dosage of vasopressor is increasing gradually, which is life-threatening; 3. Those who may die within two weeks; 4. Patients with contraindication of indwelling nasogastric tube; 5. Have a history of gastrointestinal hemorrhage.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The level of CD4 lymphocytes was detected on the 14th day after enteral nutrition.;Gastroparesis index on the 7th and 14th day after enteral nutrition;Three indicators of infection (C-reactive protein, procalcitonin and interleukin) on the 7th and 14th day after enteral nutrition;Length of stay in ICU;Gose scores at 3 and 6 months; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum prealbumin on day 14 after enteral nutrition; | — |
Countries
China
Contacts
Shenzhen Second People's Hospital