Severe neurological disease with pneumonia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Severe neurological patients with pneumonia (all patients with artificial airway), aged 18-65 years, regardless of gender; 2. It meets the diagnostic criteria of pneumonia (X-ray infiltration shadow of imaging or CT lung exudation and clinical laboratory test results); Clinical pulmonary infection score (CPIS score) >= 5 points; 3. Patients with stable hemodynamics and stable vital signs; 4. Patients or legal representatives agreed to participate in the trial and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. The difference of blood pressure and systolic pressure of both upper limbs is > 10 mmHg , the upper limb is fractured or there is an implant in the upper arm of one limb; 2. Those with severe liver and kidney dysfunction or severe basic lung diseases, such as chronic obstructive pulmonary disease and lung cancer; 3. Persons with special requirements and contraindications of body position, such as thoracic or spinal fractures, recent massive hemoptysis and history of traumatic fractures, inability to tolerate the required body position, risk of massive bleeding due to anticoagulant therapy, severe craniocerebral injury with cranial hypertension such as fracture, brain stem injury and spinal cord injury; 4. It is not suitable for this researcher to assess the risk of aspiration, and there are patients with esophagectomy, stomach resection or lung resection within half a year; 5. The attending doctor thinks that it is not suitable to participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical pulmonary infection score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood gas results;intracranial pressure;Mechanical ventilation index;Infection indicators (white blood cell count, PCT, C-reactive protein);Risk score of aspiration; | — |
Countries
China
Contacts
Guangdong Sanjiu Brain Hospital