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The clinical study of prehabilitation to improve the prognosis of frail patients undergoing gastretomy for adenocarcinoma: a single-center randomized controlled study

The clinical study of prehabilitation to improve the prognosis of frail patients undergoing gastretomy for adenocarcinoma: a single-center randomized controlled study

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100042131
Enrollment
Unknown
Registered
2021-01-14
Start date
2021-02-01
Completion date
Unknown
Last updated
2021-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastric adenocarcinoma

Interventions

Prehabilitation:Physical training: 3 times a day riding a bicycle or brisk walking for 15 minutes. Endurance training: 1. 3 times a day 10 upper limb activities (lift 2, 4, 6kg dumbbells, depending on
three groups each time
2. Lean against the wall 3 times.
Prehabilitation:Nutrition implementation:The dietitian plans the amount and variety of 3 meals a day at 30Kcal/kg/d. 20% of the total energy needs to be supplied by Enteral Nutritional Emulsion(TPF-T)
Prehabilitation:Psychological intervention:According to your own preferences, listen to light music during exercise and before sleep
Traditional group:Preoperative exercise: Quit smoking and alcohol, and instruct patients to take deep breathing exercises
the amount of activity should not be fatigued.
Traditional group:Preoperative nutrition guidance:advise to eat a high-protein, high-calorie diet.
Traditional group:Preoperative psychological care: Understand the patient's psychological expectations, family conditions, and economic status
do a good job of psychological care, for patients with psychological problems, please ask psychosomatic medical experts to guide and adjust, and increase communication.

Sponsors

Ningbo First Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: a. Gastroscopy biopsy revealed gastric adenocarcinoma; b. Not receive neoadjuvant radiotherapy and chemotherapy before surgery; c. assessed as frail (Fried Frailty Index > 2 points); d. Voluntary signed written informed consent.

Exclusion criteria

Exclusion criteria: a. Severe cardiopulmonary dysfunction; b. Too weak to accept physical exercise; c. The lower limbs extremity movement function is lacking; d. Intraoperative exploration cannot perform radical surgery (palliative resection, distant metastasis); e. Upper gastrointestinal obstruction; f. Upper gastrointestinal bleeding that requires emergency surgery; g. American Society of Anesthesiologists (ASA) classification > IV; h. cognitive impairment and cannot complete training.

Design outcomes

Secondary

MeasureTime frame
Postoperative complications above grade IIIa;Postoperative hospital stay;Total cost of hospitalization;Number of Readmission after 30 days;6-minute walk test 30 days after surgery;Number of deaths 90 days after operation;3-years disease free survival rate after surgery;3-year overall survival rate after operation;

Primary

MeasureTime frame
Comprehensive Complications Index (CCI) 30 days after surgery;

Countries

China

Contacts

Public ContactLi Hu

Ningbo First Hospital

huliwdx1982@aliyun.com+86 13777051882

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026