Effect of intraoperative intravenous injection of lidocaine on analgesia after knee arthroplasty

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100042130

Enrollment

Unknown

Registered

2021-01-14

Start date

2021-01-15

Completion date

Unknown

Last updated

2021-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain

Interventions

control group:Intravenous saline infusion

experimental group:intravenous lidocaine

Eligibility

Sex/Gender

All

Age

50 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 50 to 75 years; 2. ASA Class I-III; 3. Unilateral knee replacement under general anesthesia due to knee osteoarthritis.

Exclusion criteria

Exclusion criteria: 1. Refuse to attend; 2. Severe cardiovascular and cerebrovascular diseases; 3. Mental disorders such as epilepsy; 4. Severe renal or liver impairment; 5. Allergic to local anesthetics; 6. Heart diseases such as arrhythmia and heart block are present; 7. Other experimental studies are under way.

Design outcomes

Primary

Measure	Time frame
Postoperative pain score;Frequency of nausea and vomiting;Opioid;	—

Secondary

Measure	Time frame
Time of first exhaust;Anesthesia recovery time;Adverse events;	—

Countries

China

Contacts

Public ContactZhang Zongwang

Liaocheng People's Hospital

zwzhang68@sina.com+86 13346256809

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026