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A prospective, single arm, multicenter observational study on the compliance and effectiveness of NOAC (Rivaroxaban) in patients with high-risk atrial fibrillation

A prospective, single arm, multicenter observational study on the compliance and effectiveness of NOAC (Rivaroxaban) in patients with high-risk atrial fibrillation

Status
Recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100042086
Enrollment
Unknown
Registered
2021-01-13
Start date
2021-01-11
Completion date
Unknown
Last updated
2021-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atrial fibrillation

Interventions

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged >= 65, regardless of gender; 2. High risk patients with atrial fibrillation confirmed by clinical examination; 3. Atrial fibrillation CHADS2 score >= 2; 4. The expected survival time was more than 12 weeks; 5. Hemoglobin >= 90g / L, platelet (PLT) >= 75 x 10^9 / L, platelet (PLT) >= 75 x 10^9 / L; 6. Leukocytes (WBC) >= 3.0 x 10^9 / L, neutrophils (ANC) >= 1.5 x 10^9 / L; 7. Patients voluntarily used noac (rivaroxaban) regimen, regardless of whether they had used new anticoagulants in the past; 8. Combination therapy is allowed; 9. Sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients who can not be given oral administration; 2. Severe hepatic and renal insufficiency, or recent history of myocardial infarction (within 3 months); 3. Patients with severe uncontrolled medical diseases or acute infection (infection causes fever above 38 degrees C); 4. Pregnant or lactating women or fertile (male or female with menopause less than 1 year) are unwilling to take contraceptive measures; 5. Patients with known allergy to rivaroxaban; 6. The patients who were not suitable for the clinical trial were determined by the researchers.

Design outcomes

Primary

MeasureTime frame
adherence;

Secondary

MeasureTime frame
CHA2DS2-VASc scores;

Countries

China

Contacts

Public ContactXiaoyang Liao

West China Hospital, Sichuan University

625880796@qq.com+86 18980601359

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026