pulmonary nodules
Conditions
Interventions
Sponsors
Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Aged 18-75 years, no gender limit; (2) Patients who plan to undergo complete resection of lung nodules or needle biopsy in our hospital; (3) Preoperative thin-slice CT examination revealed a single solid nodule with a diameter of <= 3cm in the lung, and no ground-glass nodules, pneumonia and other pulmonary manifestations exist; (4) No history of malignant tumors in the past 5 years and no neoadjuvant treatment before surgery; (5) No patients with distant metastasis or pleural and ascites found in preoperative evaluation; (6) Postoperative pathological diagnosis is clear; (7) Sign the informed consent form voluntarily.
Exclusion criteria
Exclusion criteria: (1) Imaging examination cannot be performed due to pregnancy, breastfeeding, etc.; (2) No thin-slice CT examination records in the clinical center receiving treatment at the time of enrollment evaluation; (3) A history of lung infection one month before enrollment; (4) Have received blood transfusion treatment one month before enrollment, or have a history of alcohol or drug abuse; (5) Patients who cannot obtain enough blood samples (>=12ml); (6) Any conditions that are not suitable for blood sampling, such as anemia, fever, low autoimmunity, insufficiency of blood coagulation, etc.; (7) Patients with autoimmune diseases, blood system diseases, and infectious diseases.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Sensitivity;specificity; positive predictive value ;negative predictive value ; | — |
Primary
| Measure | Time frame |
|---|---|
| area under the curve of the receiver operating characteristic ;accuracy; | — |
Countries
China
Contacts
Public ContactChang Chen
Shanghai Pulmonary Hospital Affiliated to Tongji University
Outcome results
None listed