Parenteral nutritional liver disease
Conditions
Interventions
experimental group:Using 20%SMOF fat emulsion
control group:Using 20%MCT/LCT chain fat emulsion
Sponsors
Xiamen Maternal and Child Care Hospital, Women and Children's Hospital, School of Medicine, Xiamen University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Gestational age 14 days, 4.born in our hospital or transferred to our hospital within 24 hours.
Exclusion criteria
Exclusion criteria: 1.Children with congenital intrauterine infectious diseases; 2.Children with congenital malformations; 3.Children with genetic metabolic diseases; 4.Children with hyperbilirubinemia caused by intrauterine ABO or Rh hemolysis need to be treated by exchange transfusion. 5.Children with shock,severe water and electrolyte disorders and encorrected acid-base balance. 6.Children with severe liver or renal insufficiency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of parenteral nutritional liver disease; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to start using fat emulsion;Total parenteral nutrition time;Enteral-fed milk;Time to restore birth weight;invasive mechanical ventilation time;total oxygen consumption time;the incidence rate of bronchopulmonary dysplasia;the incidence rate of intraventricular hemorrhage;the incidence of retinopathy of prematurity;hospitalization time; | — |
Countries
China
Contacts
Public ContactLin xinzhu
Xiamen Maternal and Child Care Hospital, Women and Children's Hospital, School of Medicine, Xiamen University
Outcome results
None listed