Effect of retinal ON and OFF stimulation imbalance on the development of myopia

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100041898

Enrollment

Unknown

Registered

2021-01-09

Start date

2021-01-02

Completion date

Unknown

Last updated

2021-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

myopia

Interventions

ON group:White text on black background

OFF group:Black text on white background

ON/OFF group:bold text on white background

Eligibility

Sex/Gender

All

Age

8 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria of the experimental group: 1. Aged 8-11 years; 2. The refractive power progresses rapidly, and the annual refractive power change for 2 consecutive years is >0.5D; 3. 3. The range of refractive power: myopia >= 0.5D. Inclusion criteria of control group: 1. Aged >=18 years; 2. Stable refractive power, with annual refractive power change = 0.5D; 4. Voluntary participation in this study, patients need to sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Combined with strabismus, amblyopia, corneal disease, cataract, glaucoma, fundus disease and other organic eye diseases; 2. Have a family history of amblyopia, high myopia; 3. Have a history of eye surgery, trauma, or combined systemic diseases, etc.

Design outcomes

Primary

Measure	Time frame
Choroidal Thickness;	—

Secondary

Measure	Time frame
Refraction;Axial Length;Best corrected vision;	—

Countries

China

Contacts

Public ContactMin Wang

Eye Hospital of Wenzhou Medical University

18068520016@eye.ac.cn+86 18068520016

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026