Changes of clinical symptoms and ventricular size following temporary external lumbar drainage in patients with normal-pressure hydrocephalus

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100041897

Enrollment

Unknown

Registered

2021-01-09

Start date

2021-01-01

Completion date

Unknown

Last updated

2021-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hydrocephalus

Interventions

external lumbar drainage:external lumbar drainage

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1) Patient age between 40 and 85 years; 2) at least 2 symptoms of Hakim triad syndrome: Gait/balance disturbance, dementia, or urinary incontinence; 3) ventriculomegaly with an Evans index > 0.3; 4) normal CSF content and pressure (70-200 mmH2O).

Exclusion criteria

Exclusion criteria: Obstructive hydrocephalus, Chiari malformation, Parkinson disease, Alzheimers disease, decline to ELD.

Design outcomes

Primary

Measure	Time frame
INPHGS;KHS;ventricular volume;Evans index;	—

Countries

China

Contacts

Public ContactGuan Junwen

West China Hospital, Sichuan University

guanjunwen_scu@outlook.com+86 18980605821

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026