post-stroke depression
Conditions
Interventions
Sponsors
Xuanwu Hospital Capital Medical University
Eligibility
Sex/Gender
All
Age
45 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Aged 45-70 years; 2.Meeting the diagnostic criterion for cerebral infarction within 72 hours of onset; 3.Meeting the diagnostic criterion of cerebral infarction for Tan Re Fu Shi or Qi Xu Xue Yu in Traditional Chinese Medicine; 4.HAMD < 8; 5.NIHSS 0-15; 6.mRS 0-2; 7.Conscious, expressing clearly and able to cooperate with clinicians in the collection of clinical information; 8.Linving in Beijing; 9.Informed consent. Patients who meet the criterion above simultaneously can be recruited.
Exclusion criteria
Exclusion criteria: 1.WIth a history of depression; 2.With unstable vital signs; 3.Cerebral hemorrhage or mixed stroke; 4.Temporal lobe infarction lesions and with severe aphasia, agnosia, hearing or vision impairment, aphasia or dyslexic speech and cognitive impairment; 5.With serious diseases; 6.Alcoholism or substance dependence; 7.With (a history of) other psychosis or nervous system diseases resulting in impaired cognition; 8.Refusing or unable to cooperating; 9.Pregnancy; 10.With any surgery, medication, food or something that affecting gut microbiota; Patients who meet anyone of criterion above should be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Inflammatory Factors;gut microbiota;Depression-related metabolites; | — |
Countries
China
Contacts
Public ContactMiao Qu
Xuanwu Hospital Capital Medical University
Outcome results
None listed