rectal cancer & low anterior rectal resection syndrome
Conditions
Interventions
experimental group:TME + Dixon + greater omental pedicle flap transplantation
control group:TME + Dixon
Sponsors
Guangxi Medical University Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Patients with rectal adenocarcinoma confirmed by colonoscopy pathological biopsy; 2.Age: 18-70 years; 3.Preoperative endoscopic ultrasonography staging and/or local imaging staging were T1-3NX, without distant metastasis (M0). 4.Complete TME is needed for low rectal cancer (= 18 kg/m2 and <= 34 kg/m2; 7.Signed informed consent.
Exclusion criteria
Exclusion criteria: 1.Multiple primary or recurrent rectal cancer; 2.Combined abdominal and perineal resection (Mile's surgery); The reason of mental abnormality could not be assessed with the scale; 3.T1-stage rectal cancer patients meeting the criteria of transanal local resection; 4.Previous abdominal pelvic surgery or extensive abdominal adhesion; 5.Patients complicated with intestinal obstruction, intestinal perforation, intestinal bleeding and other situation requiring emergency surgery; 6.Patients with familial adenomatous polyposis, Lynch syndrome, and active inflammatory bowel disease; 7.Patients with anal fistula, perianal abscess, rectal prolapse, prolapse, anal stenosis, fecal incontinence and other anal organic or functional diseases; 8.Patients with severe liver and kidney function, cardiopulmonary function, coagulation dysfunction or combined with serious basic diseases cannot tolerate surgery; 9.Patients with consciousness disturbance or other cognitive dysfunction and a history of severe mental illness; 10.The presence of contraindications to MRI examination, such as cardiac pacemaker surgery, coronary intervention and coronary artery surgery bypass surgery; 11.Patients who are not eligible to participate in the study due to other clinical or laboratory conditions determined by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| LARS Score;Wexner Score;Anal pressure testing;Rectal defecography; | — |
Countries
China
Contacts
Public ContactMo Xianwei
Guangxi Medical University Cancer Hospital
Outcome results
None listed