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Clinical value of transesophageal echocardiography combined with right ventricular contrast echocardiography in the evaluation of PFO-related Ischemic stroke in young and middle-aged patients

Clinical value of transesophageal echocardiography combined with right ventricular contrast echocardiography in the evaluation of PFO-related Ischemic stroke in young and middle-aged patients

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100041883
Enrollment
Unknown
Registered
2021-01-09
Start date
2020-12-30
Completion date
Unknown
Last updated
2021-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

PFO-related ischemic stroke

Interventions

PFO-related ischemic stroke group vs. non stroke group:Nil

Sponsors

The Second Affiliated Hospital of Army Medical University, PLA
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: 1. The age is 18 to 55 years old. 2. The patients who were clinically diagnosed as ischemic stroke were examined by MRI and the RoPE score was more than 6. 3. Diagnosed as PFO with right-to-left shunt by TEE and cTTE, and complete data were obtained. 4. This ischemic stroke can not be explained by other reasons. 5. Be willing to participate in this study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. High-risk atherosclerotic plaques in ascending aorta, aortic arch and cervical arteries were assessed by CTA and TEE. 2. High-risk cardiac emboli, such as atrial fibrillation, coronary heart disease, thrombus, valvular vegetation, etc., are indicated by electrocardiogram and 24-hour ambulatory electrocardiogram ((Holter), TTE or TEE). 3. Other causes of ischemic stroke: arterial dissection, vasculitis, moyamoya disease, coagulation dysfunction, arteriole occlusion. 4. Complicated with severe heart, lung and other major diseases, can not cooperate well to complete the examination, or the researchers think that it is not suitable to be included in this test.

Design outcomes

Primary

MeasureTime frame
Inner diameter of PFO;Tunnel length of PFO;Classification of right-to-left shunt;Atrial Septal Aneurysm;Range of motion of primary septum; Eustachian Valve and Chiari Network;

Countries

China

Contacts

Public ContactYali Xu

The Second Affiliated Hospital of Army Medical University, PLA

xuyali1976@163.com+86 18523384936

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026