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Repetitive transcranial magnetic stimulation (rTMS) treatment for risperidone-induced hyperprolactinemia: a randomized controlled study

Repetitive transcranial magnetic stimulation (rTMS) treatment for risperidone-induced hyperprolactinemia: a randomized controlled study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100041857
Enrollment
Unknown
Registered
2021-01-08
Start date
2020-04-01
Completion date
Unknown
Last updated
2021-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperprolactinemia

Interventions

control group:pseudo rTMS

Sponsors

Fuzhou Neuropsychiatric Hospital Affiliated to Fujian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 59 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria of schizophrenia in DSM-V. 2. Patients with a course of more than 2 years; 3. Patients aged from 18 to 59 years, regardless of gender; 4. The dose of risperidone was stable for more than 4 weeks before the trial in patients who received risperidone for more than 3 months; 5. It is forbidden to use other antipsychotics, antidepressants and mood stabilizers, and it is allowed to use benzodiazepines in combination. 6. The PANSS scale was used to evaluate, and the total score reached the stable standard (PANSS 414.00uiu/ml.

Exclusion criteria

Exclusion criteria: 1. Patients with severe organic diseases or hepatic and renal dysfunction; 2. Patients with brain lesion and cranial cerebral injury history; 3. Patients with previous alcohol abuse or psychoactive substance abuse history; 4. Patients with mental retardation, personality disorders, or any other mental disorders. 5. Patients received MECT within one month of study. 6. Patients diagnosed with epilepsy, exhibited abnormal electroencephalogram activity, or reported family history with epilepsy; Patient with intracranial metallic material implant or pacemaker; 7. Patients who are pregnant, intends to be pregnant, or breastfeeding; 8. Patients who show positive results on pregnancy tests.

Design outcomes

Primary

MeasureTime frame
prolactin values;

Countries

China

Contacts

Public ContactMinjian Zheng

Fuzhou neuropsychiatric Hospital Affiliated to Fujian Medical University

27001033@qq.com+86 15960061751

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026