Alzheimer's disease
Conditions
Interventions
Normal control group, subjective cognitive decline group, mild cognitive impairment group, Alzheimer's disease group:No
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 95 Years
Inclusion criteria
Inclusion criteria: 1. All the study subjects were from the Memory Disorder Clinic of the Department of Geriatrics of Shanghai Sixth People's Hospital or advertising recruitment, signed informed consent, and collected normal controls and AD cases of different stages. According to the NIA-AA criteria to diagnose AD in dementia, Jak/Bondi criteria instead of Petersen RC criteria to diagnose MCI and Jessen criteria to diagnose SCD, the normal control group (NC group), subjective cognitive decline group, MCI group and AD in dementia were screened out ( AD group). 2. The enrolled subjects are willing to sign an informed consent form, aged 50-80, gender and education level are not limited, no anxiety, depression and other mental disorders in the past month, normal hearing and vision, cooperation in cognitive examination, no contraindications to complete MRI . MRI examination of the head showed only different degrees of brain atrophy, without lacunar infarction, patchy or diffuse leukoaraiosis.
Exclusion criteria
Exclusion criteria: A clear history of stroke, brain tumors, hydrocephalus, brain trauma and other brain diseases, serious physical diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urine formaldehyde; | — |
Countries
China
Contacts
Public ContactYing Wang
Shanghai Sixth People's Hospital
Outcome results
None listed