Sarcopenia with heart failure with reduced ejection fraction
Conditions
Interventions
Placebo Group:Placebo
Sponsors
Qilu Hospital of Shandong University
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Clinical diagnosis of heart failure, objective evidence of cardiac insufficiency proved by at least one of the following: (1) Left ventricular ejection fraction 4.0cm (or the height of the left atrium>2.5cm/m); (3) NT-proBNP>400pg/ml (>47.3pmol/l or BNP>150pg/ml). 2. For the clinical diagnosis of sarcopenia, the following conditions meet (1)(3) or all meet: (1) Grip strength (male =12s; Or simple body function assessment 18 years; 4. The patient has signed an informed consent.
Exclusion criteria
Exclusion criteria: 1.Have had a heart transplant before; 2.have tumors, chronic obstructive pulmonary disease, chronic kidney disease and other wasting diseases and fractures and other exercise-restricting diseases; 3.suffer from mental illness, including severe hysteria, involuntary persons; 4.pregnant or breastfeeding patients; 5.Test drug contraindications, allergies; 6.participated in other clinical trials in the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disability rate;Rehospitalization rate;mortality; | — |
Secondary
| Measure | Time frame |
|---|---|
| Body component analysis index;athletic ability; | — |
Countries
China
Contacts
Public ContactWang Zhihao
Qilu Hospital of Shandong University
Outcome results
None listed