Painless Gastroscopy
Conditions
Interventions
experimental group 1:remimazolam tosylate 0.2mg/kg
experimental group 2: remimazolam tosylate 0.3mg/kg
experimental group 3:remimazolam tosylate 0.4mg/kg
control group 1:Propofol medium and long chain fat emulsion
experimental group 4:high flow nasal cannular insufflation
control group 2:Ear hanging nasal catheter for oxygen inhalation
Sponsors
Jianhong Sun
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Subjects of any age and gender; 2. Patients receiving routine gastroscopy diagnosis and treatment; 3. Subjects with ASA grade I or II; 4. Subjects with 18 kg / m2 < BMI < 30 kg / m2; 5. Subjects whose gastroscope operation time is expected to be less than 15 minutes; 6. The subjects who clearly understand and voluntarily participate in the study shall sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients who need complicated endoscopic diagnosis and treatment techniques (such as cholangiopancreatography, endoscopic ultrasonography, endoscopic mucosal resection, endoscopic submucosal dissection, oral endoscopic myotomy, etc.); 2. Patients to be intubated; 3. Patients with respiratory tract management difficulties (modified Mahalanobis grade IV); 4. Patients with hypertension whose blood pressure was not controlled satisfactorily by antihypertensive drugs (sitting systolic blood pressure >= 160 mmHg, and / or diastolic blood pressure >= 100 mmHg); 5. Patients with sitting systolic blood pressure <= 90 mmHg; 6. Pregnant or lactating women; 7. Patients who are allergic or contraindicated to benzodiazepines, propofol, Dyclonine and its components; 8. Patients who are considered unsuitable to participate in this clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemodynamic inde;????;Sedation success rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Depth of anesthesia;complication;Wake up quality; | — |
Countries
China
Contacts
Public ContactJianhong Sun
Affiliated Hospital of Yangzhou University
Outcome results
None listed