Amyotrophic lateral sclerosis
Conditions
Interventions
treatment group:TMS
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. ALS patients must be over 18 years old. 2. The patients who must meet the revised El Escorial diagnostic criteria (Brooks et al., amyotrophic lateral sclerosis and other motor neuron disorders, 2000) are clinically diagnosed or suspected, that is, the patients have upper and lower motor neuron injury at more than two spinal cord segments. 3. After ECAs Chinese scale (Cognitive Scale score = 1), ALS patients have been screened with cognitive or behavioral disorders. 4. The forced vital capacity of ALS patients exceeded 75% of the predicted value. 5. Patients who have the ability to provide and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. The patients with ALS have undergone tracheotomy. 2. Patients with cochlear implant, cardiac pacemaker, metal implant, deep brain pacemaker (DBS) and vagus nerve stimulator. 3. Patients with other nervous system diseases, including brain tumors, epilepsy, brain trauma, schizophrenia or other neurodegenerative diseases. 4. ALS patients are in pregnancy or lactation. 5. Patients who have received transcranial magnetic stimulation or other cognitive function training.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the score of ECAS; | — |
Countries
China
Contacts
Public ContactXu Zhouwei
Shanghai Sixth People's Hospital
Outcome results
None listed