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Effects of rTMS on depressive state and motor function in patients with subthreshold depression after stroke

Effects of rTMS on depressive state and motor function in patients with subthreshold depression after stroke

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100041707
Enrollment
Unknown
Registered
2021-01-01
Start date
2021-01-01
Completion date
Unknown
Last updated
2021-03-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stoke

Interventions

Treatment Group:rTMS was used in addition to conventional treatment
control group:conventional treatment

Sponsors

General Hospital of Western Theater Command of PLA
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. All the subjects who met the diagnostic criteria of stroke formulated by the fourth national Cerebrovascular Disease Conference of Chinese Medical Association in 1995 were confirmed by brain CT or MRI scan. The patients with stroke should be diagnosed by doctors with the title of deputy chief physician or above; 2. The subjects who met the diagnostic criteria of subthreshold depression were all 18-80 years old, with stable condition, clear mind, no obvious understanding disorder, and were right-handed, and could cooperate to complete the test; 3. Subjects with CES-D score >= 16; HAMD-17 score: 7 <= HAMD-17 total score < 17; 4. Those subjects whose clinical status is suitable for rTMS as the treatment of subthreshold depression; 5. Subjects who have no history of using psychoactive substances; volunteers who participate in this study and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with clinically confirmed depression, previous mental illness or organic mental disorder; 2. Patients with severe liver and kidney damage, severe arrhythmia or cardiac insufficiency, severe cognitive impairment, and severe aphasia; 3. Patients with depressive episode caused by psychoactive substance and non addictive substance; patients with strong suicide attempt or behavior; 4. Patients who are participating in other clinical trials; other conditions judged by the researchers not suitable for inclusion in the observation; 5. Patients taking estrogen drugs; lactating and pregnant women; 6. Patients who had received rTMS or electroconvulsive therapy within one year.

Design outcomes

Primary

MeasureTime frame
CES—D;HAMD;FMA;MBI;

Countries

China

Contacts

Public ContactLiu Jiancheng

General Hospital of Western War Zone of PLA

422327057@qq.com+86 18982237667

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026