Nasolabial fold
Conditions
Interventions
A:The left side was injected with the traditional deep and shallow layer method, while the right side was injected with the ligament method
B:The right side was injected with the traditional deep and shallow layer method, while the left side was injected with the ligament method
Sponsors
Guangdong Second People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Subjects older than or equal to 18 years old; 2. Patients who intend to correct bilateral nasolabial fold were evaluated as moderate to severe nasolabial fold (WSRs grade 2-3); 3. Subjects who voluntarily participated in the study and signed informed consent; 4. The subjects who can communicate well with the researchers and comply with the requirements of the whole trial can return to the hospital for reexamination on the follow-up date.
Exclusion criteria
Exclusion criteria: 1. Women who were pregnant or breast-feeding or planned to be pregnant during the study period; 2. Patients who have received facial cosmetic surgery; 3. Subjects with known allergies to any study drug or anesthetic used in the study; 4. Patients with anticoagulant therapy or antiplatelet therapy (such as non steroidal anti-inflammatory drugs, aspirin, vitamin E, etc.) or history of hemorrhagic disease within 2 weeks before treatment; 5. Patients with unhealed inflammation or other related diseases at the site to be treated, such as infection, psoriasis and herpes zoster; 6. Patients with obvious facial asymmetry (such as big and small eyes, etc.); 7. Subjects who plan to undergo any other facial plastic surgery or cosmetic operation (e.g., laser or chemical skin change, acupuncture, facial lifting, radiography, etc.) on the site to be treated throughout the study period; 8. Patients with local or systemic bacterial infection in acute stage that can not be effectively controlled.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wrinkle Severity Rating Scale;Global Aesthetic Improvement Scale; | — |
Countries
China
Contacts
Public ContactShengkang Luo
Guangdong Second People's Hospital
Outcome results
None listed