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Clinical randomized controlled study on the soft tissue augmentation with autologous soft tissue, acellular dermal matrix and collagen matrix around teeth / implants

Clinical randomized controlled study on the soft tissue augmentation with autologous soft tissue, acellular dermal matrix and collagen matrix around teeth / implants

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100041688
Enrollment
Unknown
Registered
2021-01-01
Start date
2020-12-28
Completion date
Unknown
Last updated
2021-03-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Soft tissue insufficient around teeth/implants

Interventions

Autologous Soft Tissue Graft Group:Augmentation with autologous soft tissue flap
CM Group:Augmentation with CM

Sponsors

Stomatological Hospital of Shandong
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: If any of the following is "no", the patient cannot accept the trial. (1) Aged >= 18 and <= 70 years, regardless of gender; (2) The width of keratinized gingiva was less than 2 mm; (3) Plaque index and bleeding percentage were less than 20%.

Exclusion criteria

Exclusion criteria: If any of the following is "yes", the patient cannot accept the trial. (1) The patients who did not receive perfect periodontal basic treatment before operation; (2) Patients with infection at the treatment site; (3) Severe abnormal liver and kidney function; (4) Poor control of blood glucose (fasting blood glucose > 7.0 mmol / L); (5) Patients with uncontrolled and stable severe hypertension (systolic blood pressure >= 160 mmHg and / or diastolic blood pressure >= 100 mmHg); (6) Patients who need bone augmentation at the same time; (7) Smokers; (8) Pregnancy; (9) Coagulation disorders or taking anticoagulant drugs; (10) Other contraindications to oral and / or surgical treatment.

Design outcomes

Primary

MeasureTime frame
Volume of recipient graft after soft tissue augmentation;

Secondary

MeasureTime frame
alveolar bone horizontal level at operation site;subjective functional discomfort rate;Duration of subjective functional discomfort;Width of keratinized gingiva;Gingival index;Plaque index;Bleeding of probing;

Countries

China

Contacts

Public ContactWen Yong

Stomatological Hospital of Shandong

wenyong@sdu.edu.cn+86 13305412356

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026