Diabetes Mellitus
Conditions
Interventions
Diabetes+Dexmedetomidine:Dexmedetomidine is infused intravenously at the rate of 0.4 ug/kg/h until 30 minutes before the end of the operation.
Diabetes+Control:The control group was injected with normal saline at the same rate as the DD group
Non diabetes+Dexmedetomidine:Dexmedetomidine is infused intravenously at the rate of 0.4 ug/kg/h until 30 minutes before the end of the operation.
Non diabetes+Control:The control group was injected with normal saline at the same rate as the DD group
Sponsors
Shaanxi Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Accord with the diagnostic criteria of diabetes; 2. There was no significant abnormality in blood routine, liver and kidney function, electrolytes, myocardial enzymes and acid-base balance disorder; 3. Fasting blood glucose = 65 and < 80 years; 7. There was no history of chemotherapy and radiotherapy before operation, and no hormone and immune drugs were used.
Exclusion criteria
Exclusion criteria: 1. Serious circulatory, respiratory, digestive and urinary diseases; 2. Drug addicts or drug abusers, and those who are allergic to narcotic drugs; 3. There are contraindications to operation or anesthesia; 4. Serious arrhythmia; 5. Random blood glucose > 11.1mmol/l; 6. Install temporary or permanent pacemaker; 7. Poor compliance; 8. Death or withdrawal from treatment; 9. Mental patients and critically ill patients; 10. Incomplete clinical data can not determine the efficacy and safety.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| High sensitivity troponin I; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of cardiovascular events during and within 30 days after operation; | — |
Countries
China
Contacts
Public ContactChang Jianhua
Shaanxi Provincial People's Hospital
Outcome results
None listed