Minimal change nephrotic syndrome
Conditions
Interventions
Oral prednisone:oral prednisone
Oral prednisone combined with thymosin 1 group:Thymosin 1 was injected
Sponsors
Affiliated Hospital of Guangdong Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. The patients who voluntarily participated in this study and signed the informed consent; 2. Patients aged 18-70 years; 3. Patients diagnosed as minimal change nephrotic syndrome by pathology; 4. Patients with complete remission and recurrence (urinary protein > 3.5g/d or urinary protein / creatinine 3500mg / g) after standard hormone therapy.
Exclusion criteria
Exclusion criteria: 1. Those patients with severe infection; 2. Patients with secondary glomerular diseases; 3. Patients with severe gastrointestinal complications or other reasons who can not accept oral drug treatment; 4. Those patients with hormone and Thymosin contraindications and intolerance; 5. Patients with mental disorder and poor compliance; 6. Patients with severe primary diseases such as cardiovascular, cerebrovascular, endocrine and hematopoietic system; 7. Pregnant and lactating women; 8. The patients who met the inclusion criteria of the study were withdrawn from the study due to their personal wishes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The recurrence rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Infection rates; | — |
Countries
China
Contacts
Public ContactYao Cuiwei
Guangdong Medical University
Outcome results
None listed