cervical cancer
Conditions
Interventions
Radiosensitivity group vs Nonsensitivity group:Nil
Sponsors
Department of Tumor Radiotherapy, the First Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Before the start of any study related procedures, patients have fully understood the study and voluntarily signed a written informed consent form; (2) The age ranged from 18 to 75 years; (3) Patients with cervical cancer (2018 FIGO stage) IB3, II, III and IVA were confirmed by pathology; (4) Voluntarily accept radical radiotherapy and chemotherapy for cervical cancer; (5) KPS > 70; RTOG independent recursive rating index (RPA) = 6 months; (7) The function of each organ was basically normal (without continuous supportive treatment, laboratory examination results within one week before enrollment): neutrophil > 1.5 * 10^9 / L, platelet > 100 * 10^9 / L, hemoglobin > 9.0 g / dl; bilirubin was normal or < 1.5 * ULN; AST (SGOT), ALT (SGPT) < 2.5 * ULN (if liver metastasis < 5 * ULN); serum creatinine < 1.5 * ULN.
Exclusion criteria
Exclusion criteria: (1) Previous pelvic radiotherapy; (2) Previous surgical treatment for cervical cancer; (3) Pregnant; (4) Patients with severe and uncontrolled organic disease or infection, such as decompensated heart, lung and renal failure, which can not tolerate radiotherapy, targeted therapy or chemotherapy; (5) The second primary tumor; (6) Major surgery within 4 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ORR; | — |
Secondary
| Measure | Time frame |
|---|---|
| one-year PFS rate; | — |
Countries
China
Contacts
Public ContactJuying Zhou
The First Affiliated Hospital of Soochow University
Outcome results
None listed