Study on the effect of the endoscopic transnasal resection of the pituitary adenoma combined with selective resection of the peritumoral anterior pituitary gland in patients with Cushing's disease

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100041629

Enrollment

Unknown

Registered

2021-01-01

Start date

2021-01-01

Completion date

Unknown

Last updated

2021-03-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pituitary adenoma

Interventions

Intervention Group:endoscopic transnasal resection of the pituitary adenoma combined with selective resection of the peritumoral anterior pituitary gland

Control Group:Routine transnasal neuroendoscopic pituitary tumor resection

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 18 ~ 70 years; 2. Confirmed with Cushing's disease; 3. Need surgery.

Exclusion criteria

Exclusion criteria: 1. Patients with severe heart, lung, liver, or CNS disease, coagulopathies and other medical conditions that would preclude surgical treatment; 2. Pregnant or lactating women; 3. Female patients who plan toto become pregnant in the next 2 years.

Design outcomes

Primary

Measure	Time frame
ACTH and cortisol in blood;	—

Secondary

Measure	Time frame
Pituitary hormone;MRI of sellar area;Blood pressure, serum glucose and blood electrolytes;Pathology of excised tissue;Quality of life scale score;	—

Countries

China

Contacts

Public ContactQi Li

The First Affiliated Hospital of Xi'an Jiaotong University

kakasurgery@qq.com+86 13909265968

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026