Chronic obstructive pulmonary disease, Sarcopenia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Mild and moderate Patients with chronic obstructive pulmonary disease: FEV1/FVC = 50%pred; (2) Stable period of chronic obstructive pulmonary disease; (3) Possible sarcopenia: recommended according to the 2019 Asian expert consensus; (4) Subjects voluntarily participate and sign informed consent.
Exclusion criteria
Exclusion criteria: (1) Cognitive impairment; (2) Diagnosed with cardiovascular, metabolic or renal disease and any symptoms or signs associated with cardiovascular, metabolic or kidney disease; (3) Complicated with pulmonary bullae, pneumothorax and malignant tumor; (4) Contraindications to exercise: for example, there is a limb fracture or major operations in the last 3 months; (5) Unable to walk independently, such as in a wheelchair or using a walker; (6) Subjects participated in other regular exercise or studies 3 months prior to enrollment; (7) Subjects have metal implants in their bodies cannot participate in body composition measurement by Human composition analyzer.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| health outcomes in patients with chronic obstructive pulmonary disease;Skeletal muscle mass and function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Others (such as adverse events, compliance, etc.); | — |
Countries
China
Contacts
School of Nursing and Rehabilitation, Shandong University